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Molecular Technologist, Solid Tumor (3rd Shift)

Caris Life Sciences

Caris Life Sciences

Phoenix, AZ, USA
Posted on Saturday, June 1, 2024

Position Summary

The Molecular Technologist is responsible for performing various molecular techniques that include, but are not limited to, formalin-fixed paraffin-embedded tissue macro-dissection, RNA/DNA extractions, PCR, DNA methylation analysis, equipment maintenance, laboratory inventory, sample tracking, ordering supplies and receiving packages. This position works under the direction of the supervisor and follows standard laboratory procedures and policies.

Job Responsibilities

  • Sample preparation, including blood centrifugation, plasma processing and buffy coat extractions.

  • Performs RNA and DNA extractions for daily molecular testing and ensures correct patient labeling.

  • Performs molecular techniques such as real-time PCR, DNA Methylation analysis and Next-Generation Sequencing.

  • Prepares Corrective and Preventive Action (CAPA) documents for nonconformance events observed during the pre-analytical, analytical, and post-analytical clinical laboratory testing.

  • Performs Proficiency Testing in a timely manner and submits results to Supervisors.

  • Conducts validation testing for new clinical assays.

  • Tracks, enters, and monitors patient files using the Laboratory Information System.

  • Maintains laboratory equipment, including completing logs and maintenance, i.e. clean, sterilize, maintain, and shut down laboratory equipment, accessories, and instruments used in research experiments, daily and weekly as required.

  • Unpacks reagent orders as received; logs them in the reagent database; creates labels, tracking documentation, and QC forms; and stores them in the proper location and conditions.

  • Accepts other duties as assigned.

  • Each individual performs only those high complexity tests that are authorized by the laboratory director and require a degree of skill commen­surate with the individual’s education, training or experience, and technical abilities.

  • Each individual performing high complexity testing must:

  • Follow the laboratory’s proce­dures for specimen handling and proc­essing, test analyses, reporting and maintaining records of patient test results;

  • Maintain records that dem­onstrate that proficiency testing sam­ples are tested in the same manner as patient specimens;

  • Adhere to the laboratory’s quality control policies, document all quality control activities, instrument and pro­cedural calibrations and maintenance performed;

  • Follow the laboratory’s estab­lished policies and procedures when­ever test systems are not within the laboratory’s established acceptable lev­els of performance;

  • Be capable of identifying problems that may adversely affect test perform­ance or reporting of test results and ei­ther must correct the problems or im­mediately notify the general super­visor, technical supervisor, clinical consultant, manager or director;

  • Document all corrective actions taken when test systems deviate from the laboratory’s established perform­ance specifications; and

  • Perform high complexity testing under the onsite, direct supervision of a general supervisor as defined in the CLIA regulations.

Required Qualifications

  • Bachelor’s degree in a science field is required.

  • Demonstrated skills in technical data interpretation and ability to troubleshoot.

  • Proficient in Microsoft Office Suite, specifically Word, Excel, Outlook, general working knowledge of Internet for business use, and skilled in operating office equipment.

  • Conditions of Employment: Individual must successfully complete pre-employment process, which includes criminal background check, drug screening and reference verification.

Preferred Qualifications

  • Master’s degree in a science field is preferred.

  • RNA and DNA extraction experience.

  • Knowledge of laboratory safety procedures for biohazards and chemicals, as well as quality control procedures and regulations.

Physical Demands

  • Will work at a computer some of the time as well as need to keep inventory and ordering records requiring the use of copiers and PDF scanners.

  • Visual acuity and analytical skill to distinguish fine detail. Ability to pass a visual color discrimination test.

  • Manual dexterity to use common laboratory equipment and perform sterile techniques as required.

  • Must possess ability to sit and/or stand for long periods of time.

  • Must possess ability to perform repetitive motion.

  • Ability to lift up to 30 pounds.

  • May be required to handle and/or may have exposure to blood-borne pathogens, extreme temperatures, high noise levels, fumes and bio-hazardous material/chemicals including formaldehyde, xylene, Clorox bleach, DAB and alcohol, which emit fumes. The formaldehyde, xylene, and DAB are carcinogenic.


  • 3rd Shift Hours: 9:30pm-8am

  • This position may require evenings/nights, weekends and Holidays.

This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.

Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.