At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.

We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do.

But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose.

Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.

Position Summary
Senior Software Engineer – Clinical Systems roles at Caris requires collaborating with various team members, including Software Engineers, Architects, Engineering Managers, Directors, Product Managers (PMs), Software Quality Assurance (SQA) specialists, and Business Analysts (BAs), to develop both internal and external software and data solutions. Engineers are responsible for every phase of the application development lifecycle and possess comprehensive knowledge of enterprise data flow.

Key responsibilities include working closely with cross-functional teams to build software applications that meet stakeholders’ needs, covering multiple lab workflows. They engage in all stages of the system’s lifecycle, leveraging expert knowledge of enterprise data processes. The role demands strong coding skills in Java, Spring Boot, utilizing front-end frameworks such as Vue and React to address complex business requirements. Additionally, they apply web design expertise to solve intricate business challenges effectively. A deep understanding of databases and database concepts, including proficiency in Standard Query Language (SQL), is essential.

This role involves designing and implementing scalable, secure, and interoperable systems that integrate with lab workflows and data pipelines. Reporting to the Senior Manager of Clinical Software Engineering, they will collaborate across teams to deliver high-impact solutions aligned with business and regulatory goals.

Job Responsibilities

• Work closely with Software Engineering Manager and Business Stakeholders to deliver worldclass applications for Lab workflows including Pathology, Genetics and Quality Evidence teams.

• Observe HIPAA (Healthcare Insurance Portability and Accountability Act) rules and regulations as laid down by the HIPAA Compliance Officer. Follow organizational information security policies to safeguard company data and systems.

• Collaborate with team in gathering new requirements, designing technical implementation and successfully converting these designs into practical code and functional programs that fulfill user requirements

• Test the developed functionality and support the Quality Assurance Team to ensure the solution meets user requirements and is defect-free.

• Monitor incident tickets, determine resolution priority by working with users, and document the resolution for future reference.

• Perform code reviews and offer constructive feedback to team members. Collaborate with cloud operations and DevOps team members to support releases effectively.

• Provide technical/engineering support for existing applications from code delivery until retirement, including performing code fixes for documented defects.

• Consistently learn and implement best practices to enhance application quality and boost performance. Stay informed about the latest trends and advancements in software development.

• Analyze and solve complex technical problems, ensuring code quality, performance, and scalability.

• Collaborate with other departments such as product management and quality assurance to ensure seamless product delivery.

• Assist management in providing accurate timeline and resource estimates, as well as delivery details, to successfully release products.

• Mentor and coach junior developers to improve their skills and productivity.

• Assist in performing other related duties and special projects as required, and accept other duties as assigned.

Required Qualifications

• Bachelor’s degree in computer science, software engineering, or a similar discipline.

• 5-7 years of proficiency in core Java concepts and enterprise-level application development, with experience using frameworks like Spring Boot.

• Understanding of Python programming and experienced in JavaScript for both front-end and back-end development, including working knowledge of Vue.js or React/SPA.

• Proficient in designing interactive applications with a focus on user engagement and seamless user experience.

• Excellent knowledge of relational databases, SQL and ORM technologies (MySQL or Postgres)

• Comprehensive grasp of software design patterns, data structures, algorithms, and REST API design and integration. Implement robust authentication mechanisms, encryption, and other security protocols as part of software development practices following industry-standard protocols like OIDC/OAuth 2.

• Skilled in writing clean, maintainable, and efficient code with iterative delivery mindset.

• Extensive experience in writing, executing, and maintaining unit tests to ensure code quality and reliability.

• Work with Docker and Kubernetes (preferred) for containerization and orchestration.

• Proficient with version control systems like Git and familiar with CI/CD pipelines and DevOps practices.

• Proficient in cloud services, including AWS Lambda, SNS/SQS integration, and S3 integration, as well as analogous features in GCP or Azure.

• Understands agile methodologies and thrives in an Agile environment.

• Exhibits excellent problem-solving skills and analytical thinking.

• Possesses strong communication skills and works well collaboratively in team-oriented environments.

Preferred Qualifications

• Java EE Certification.

• Experience working on AI tools like Cursor AI.

• Experience with applications build process leveraging tools like Maven, etc.

• Extensive experience in crafting complex SQL queries for both MySQL and PostgreSQL databases, ensuring data efficiency and integrity.

• Demonstrated capability to independently diagnose, analyze, and resolve complex issues related to application software. This includes identifying root causes, implementing effective solutions, and ensuring minimal disruption to operations, all while working without direct supervision.

• Skilled in ensuring HIPAA compliance, improving patient outcomes, and maintaining quality assurance standards, while adhering to regulatory requirements. This expertise promotes accountability and enhances satisfaction among both end-users and patients.

Physical Demands

• Ability to sit, stand, and work at a computer for extended periods.

Training

• All job specific, safety, and compliance training are assigned based on the job functions associated with this employee.

Other

• This position requires periodic travel and flexible availability, including some evenings, weekends, and/or holidays.

• The role may require after-hours response to emergency issues. There are also occasionally scheduled on-call duties that necessitate responding to technical emergencies beyond assigned job responsibilities.

Conditions of Employment: Individual must successfully complete pre-employment process, which includes criminal background check, drug screening, credit check ( applicable for certain positions) and reference verification.

This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.

Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.