At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.

We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do.

But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose.

Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.

Position Summary
The Construction Project & Program Manager oversees the planning, design, and execution of multiple construction projects within a life sciences environment, including laboratories, GMP manufacturing spaces, and research facilities. This role combines project-level oversight with program-level coordination to ensure alignment with organizational goals, regulatory compliance, and operational readiness.

Job Responsibilities
Program Management

• Develop and manage a portfolio of construction projects supporting strategic initiatives.
• Align project objectives with corporate priorities and scientific operations.
• Establish governance frameworks, reporting structures, and risk management strategies.
• Develop standards for the development of Architecture and Engineering solutions.
• Monitor program performance metrics and ensure resource optimization across projects.

Project Management

• Plan and execute individual construction projects from concept through commissioning.
• Coordinate with architects, engineers, and scientific stakeholders to meet technical and compliance requirements.
• Manage budgets, schedules, communications, financial reporting, and vendor contracts for each project.

Regulatory & Compliance Oversight

• Ensure adherence to FDA, GMP, ISO, and other regulatory standards.
• Implement environmental health and safety protocols throughout construction.
• Ensure all projects are aligned with Caris Quality Management System expectations and protocols.
• Deliver required documentation for Construction Qualifications, Validation, and protocols.

Stakeholder Engagement

• Serve as the primary liaison between facilities, research teams, executive leadership, and contractors.
• Provide transparent communication on program status, risks, and milestones.

Risk & Quality Management

• Identify and mitigate risks across the program portfolio.
• Ensure quality standards and validation requirements are met for all facilities.
• High degree of safety management throughout the project.

Required Qualifications

• Bachelor’s degree in Construction Management, Engineering, or related field.
• 7+ years of experience in construction and program management within life sciences, pharmaceutical, or biotech environments.
• Strong knowledge of GMP and laboratory infrastructure.
• Proficiency in program and project management tools (MS Project, Procore, Smartsheet).
• Excellent leadership, communication, collaboration, and strategic planning skills.
• Proficient in Microsoft Office Suite, specifically Word, Excel, Outlook, and general working knowledge of Internet for business use.

Preferred Qualifications

• Masters Degree

Physical Demands

• Ability to function in dynamic job site environments that may include climbing, lifting, and variable footing situations.

Training

• All job specific, safety, and compliance training are assigned based on the job functions associated with this employee.

Other

• This position requires periodic travel and some evenings, weekends and/or holidays.
• Job may require after-hours response to emergency issues.
• Periodically scheduled on-call may require after-hours response for technical emergencies not explicitly related to assigned job responsibilities.
• At times may be required to work weekends/holidays.

Conditions of Employment: Individual must successfully complete pre-employment process, which includes criminal background check, drug screening, credit check ( applicable for certain positions) and reference verification.

This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.

Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.