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Engineer, Gene Assembly

DNA Script

DNA Script

le kremlin-bicêtre, france
Posted on Tuesday, June 25, 2024

DNA Script

DNA Script is a leading company in the production of nucleic acids for genomic, synthetic biology and biopharmaceutical applications.

Our clean, efficient Enzymatic DNA Synthesis (EDS) technology, implemented on a benchtop instrument (the SYNTAX), accelerates innovation in life science and biotechnology through the decentralization of rapid, on demand and high quality DNA synthesis.

Our approach builds upon nature's billions of years of evolution in enzymatically synthesizing DNA, setting new standards for assembling nucleic acids to accelerate scientific discovery and DNA/RNA production in disciplines with profound impacts upon humanity.

DNA Script has a broad stable of high quality investors and is capitalized to continue its progress to full commercialization of the technology and products. We are building an organization across our two sites, in Paris and San Francisco, with the talent, skills and attitude to achieve our mission: to unlock the power of “DNA-write”.

This is an opportunity for a dynamic individual to join an international and highly skilled team, and to make significant contributions to commercializing a technology with far-reaching potential across the biological sciences and beyond.

The Role

We are looking for talented biotechnology engineer to strengthen the Gene Assembly. She/he will be participating in various projects aiming to develop the company core technology, qualifying the synthetic DNAs and evaluating their use and performance in multiple molecular biology applications. The ideal candidate should have significant experience in multiple molecular biology techniques and should be able to interact efficiently with many different teams, in particular bio-informatics/data science, synthesis and NGS platforms. We are seeking for an individual who is well organized, pro-active, detail oriented, enjoys problem solving and able to work in a multi-disciplinary role. The successful candidate will have a strong molecular biology background with an interest in leading their own research projects and contributing to the development of internal processes.

Main Responsibilities:

  • Develop and optimize molecular biology protocols for the characterization of DNA Script products, in collaboration with researchers and engineers of the Gene Assembly team and other.
  • Define project experimental plans, perform experimentation, and ensure in-depth analysis of data.
  • Guarantee a good documentation of experiments/results and ensure a high-quality reporting, oral and written.
  • Work collaboratively within the team and with other groups across the company, collaborate with external partners.
  • Engage in good laboratory/documentation practice, write Standard Operation protocols (SOP) and enforce correct use.
  • Participate to the good organization of the R&D laboratory
  • Actively contribute towards critical company milestones with a willingness to work outside immediate area of expertise when required.

Experience:

Essential

  • Master’s or Engineering degree in the field of molecular biology, biotechnology or similar.
  • 2 to 5 years of experience in molecular biology.
  • Strong knowledge of usual and advanced molecular biology techniques: DNA/RNA purification and characterization methods, cloning, PCR, q-PCR, sequencing (Sanger, NGS), gene editing, molecular probes….
  • Very comfortable and happy at the bench.
  • Experience in working with bio-informatic pipelines, software, data analysis tools.
  • Down-to-earth mindset focused on finding simple solutions to complex problems.
  • Willingness to work on automated systems (Ep Motions, Opentrons…)
  • Excellent organizational, analytical and systematic troubleshooting skills.
  • Excellent communication, reporting and interpersonal skills
  • Fluent in English, intermediate French language level.
  • Very positive mindset, highly motivated and pro-active

Desirable

  • Experience in automation, use of liquid handling systems (especially Hamilton systems).
  • Basic coding skills or willing to learn.
  • Experience in nucleic acid synthesis and/or gene assembly protocols.
  • Experience in development of innovative processes and optimization.

Miscellaneous

  • Job located in Kremlin Bicêtre, France
  • Start date: As soon as possible.

Recruitment Process:

  • Initial screening with the hiring manager
  • Day interview at the office (or remote) with the manager, cofounders, HR and the rest of the team
  • Reference Checks
  • Timing: 2-3 weeks